AM I NEXT? NO LOVE AT AGC BIOLOGICS

Seattle, Washington-based AGC Biologics, a contract development and manufacturing company for biopharmaceuticals, has announced plans to lay off employees located at its Longmont, Colorado, and Boulder, Colorado manufacturing facilities, which are being considered for sale. Operations will be transferred to the company's Seattle facilities.

The reduction in force will impact 278 employees. The layoffs are scheduled to be completed by December 31, 2025

According to a company spokesperson, "This decision is part of a broader strategy to divest from large-scale mammalian production facilities and refocus on core strengths such as midscale mammalian manufacturing, microbial production, and cell and gene therapy services.

Change is coming. There will always be a tomorrow, no matter how much you may try to ignore it. There are no guarantees in life, nor promises of a bright future. We see good people being laid off through no fault of their own. Just because something terrible hasn't happened yet doesn't mean it won't. It can happen to anyone, at any time, anywhere. No one is guaranteed to wake up tomorrow and still have a job by evening. While many employees can read the writing on the wall, why do most assume it’s targeted at someone else? Are you now wondering, Am I Next?

AM I NEXT? NO LOVE AT IOVANCE BIOTHERAPEUTICS

San Carlos, California-based Iovance Biotherapeutics, a biotechnology company focusing on developing tumor-infiltrating lymphocyte therapies against cancer, has announced a 19% reduction in its workforce to conserve cash.

The reduction will impact 230 employees, including both full-time employees and contractors.

According to a spokesperson, “After careful evaluation of our long-term goals, operational needs, and resources, we have implemented a strategic restructuring that includes a selective reduction in force to support our mission to innovate, develop and deliver TIL cell therapy to patients in need. This restructuring will extend our cash runway, and we remain on track to deliver on our financial goals.”

Change is coming. There will always be a tomorrow, no matter how much you may try to ignore it. There are no guarantees in life, nor promises of a bright future. We see good people being laid off through no fault of their own. Just because something terrible hasn't happened yet doesn't mean it won't. It can happen to anyone, at any time, anywhere. No one is guaranteed to wake up tomorrow and still have a job by evening. While many employees can read the writing on the wall, why do most assume it’s targeted at someone else? Are you now wondering, Am I Next?

AM I NEXT? NO LOVE AT ADAPTIMMUNE

Philadelphia, Pennsylvania-based Adaptimmune, a biopharmaceutical company that develops T cell therapies against cancer, has announced a major restructuring, including the sale of intellectual property to Louisville, Kentucky-based US WorldMeds Partners, and a 62% reduction in its workforce.

The layoffs will impact approximately 300 employees. Earlier reductions included a 29% workforce reduction completed in early 2025. It is not known how many employees will be hired by US WorldMeds.

"As part of the Restructuring, Elliot Norry, our Chief Medical Officer, and Cintia Piccina, our Chief Commercial Officer, will cease to be employed by Adaptimmune LLC as of August 8, 2025, and Joanna Brewer, our Chief Scientific Officer, will cease to be employed by Adaptimmune Limited as of August 31, 2025. As previously disclosed, Gavin Wood, our Chief Financial Officer, will cease to be employed by Adaptimmune Limited as of August 31, 2025."

CEO Adrian Rawcliffe noted, “Adaptimmune has been at the forefront of solid tumor cell therapy and delivering groundbreaking treatments to patients for more than a decade. We were the first company to obtain a marketing authorization for an engineered TCR T-cell therapy, TECELRA, and we have a second cell therapy, lete-cel, with approval anticipated in 2026. However, given the financial situation of the Company, it is clear that securing the right strategic option was critical to maximize value for all of our stakeholders and, importantly, ensure our patients continue to receive TECELRA. After an extensive review of all strategic alternatives available to Adaptimmune, we are convinced that this transaction represents the best path forward for Adaptimmune, our patients, and stakeholders.”

Change is coming. There will always be a tomorrow, no matter how much you may try to ignore it. There are no guarantees in life, nor promises of a bright future. We see good people being laid off through no fault of their own. Just because something terrible hasn't happened yet doesn't mean it won't. It can happen to anyone, at any time, anywhere. No one is guaranteed to wake up tomorrow and still have a job by evening. While many employees can read the writing on the wall, why do most assume it’s targeted at someone else? Are you now wondering, Am I Next?